*Department of Surgery, University of Pennsylvania School of Medicine and Philadelphia Veterans Affairs Medical Center, Philadelphia, PA †Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA ‡Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA §Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA ¶Departments of Biomedical Engineering and Chemistry, Emory University, Atlanta, GA ||Department of Chemistry, Purdue University, West Lafayette, IN.